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109269 Papanicolaou's solution 3d polychromatic solution EA 65

for cytology

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
109269
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      		 Glass bottle 100 ml
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      1.09269.2500
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          		 Glass bottle 2.5 l
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          Description
          Catalogue Number109269
          DescriptionPapanicolaou’s solution 3d polychromatic solution EA 65
          OverviewPapanicolaou’s solution 3d polychromatic solution EA 65 - for cytology, is a ready-to-use solution used for human-medical cell diagnosis and serve the purpose of the cytological investigation of sample material of human origin, for example, gynecological and clinico-cytological specimen materials. Papanicolaou’s technique is the most used staining procedure for cytological specimen is and is intended for the the staining of exfoliative cells in cytological specimens. In the first step, the cell nuclei are stained either progressively or regressively with a hematoxylin solution, (Hematoxylin solution modified acc.to Gill II, (Cat.no. 105175), Papanicolaou’s solution 1a Harris hematoxylin solution, (Cat.no. 109253) or Papanicolaou’s solution 1b Hematoxylin solution S, (Cat.no. 109254)). Nuclei are stained blue to dark violet. In the progressive hematoxylin staining method, staining is carried out to the endpoint, after which the slide is blued in tapwater. With the regressive method the material is over-stained and the excess of staining solution is removed by acid rinsing steps, followed by the bluing step. The structures of nuclei are more differentiated and better visible by the regressive method. The second staining step is cytoplasmic staining by orange staining solution (Papanicolaou’s solution 2b Orange II solution, Cat. no. 1106887 or Papanicolaou’s solution 2a Orange G solution (OG6), Cat. no. 106888), especially for demonstration of mature and keratinized cells. The target structures are stained orange in different intensities. In the third staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown, (Papanicolaou’s solution 3a polychromatic solution EA 31, (Cat.no 109271), Papanicolaou’s solution 3b polychromatic solution EA 50, (Cat.no. 109272), Papanicolaou’s solution 3c polychromatic solution EA 65,(Cat.no. 109270), or Papanicolaou’s solution 3d polychromatic solution EA 65, (Cat.no.109269). The polychrome solution is used for demonstration of differentiation of squamous cells. Papanicolaou’s solution 3d polychromatic solution EA 65 gives a delicate, blue-green-pinkish staining result in clinical specimen material.
          The 100 ml bottle provides 300 - 400 stainings. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
          References
          Product Information
          HS Code3212 90 90
          Quality LevelMQ400
          Applications
          Applicationfor cytology
          Biological Information
          Physicochemical Information
          Density0.85 g/cm3 (20 °C)
          Flash point17 °C
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H225: Highly flammable liquid and vapour.
          H317: May cause an allergic skin reaction.
          H319: Causes serious eye irritation.
          Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
          P233: Keep container tightly closed.
          P240: Ground and bond container and receiving equipment.
          P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
          P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
          Signal WordDanger
          Storage class3 Flammable liquids
          WGKWGK 2 obviously hazardous to water
          Disposal1
          Strongly contaminated halogen-free organic solvents: container A.
          Safety Information
          Categories of dangerhighly flammable
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 1170 , 3, II
          Declaration (transport by air) IATA-DGRUN 1170 , 3, II
          Declaration (transport by sea) IMDG-CodeUN 1170 , 3, II
          Supplemental Information
          Specifications
          Suitability for microscopy (Vaginal smear)passes test
          Nucleiblue to dark violet
          Cyanophilic Cytoplasm (basophilic)blue-green to blue-grey
          Eosinophilic Cytoplasm (acidophilic)pink to red-violet
          Global Trade Item Number
          Catalogue Number GTIN
          1.09269.0100 04022536112787
          1.09269.2500 04022536112800

          Documentation

          Papanicolaou's solution 3d polychromatic solution EA 65 SDS

          Title

          Safety Data Sheet (SDS) 

          Papanicolaou's solution 3d polychromatic solution EA 65 Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1.09269.0100 Glass bottlePDF Specification Document
          1.09269.2500 Glass bottlePDF Specification Document

          Related Products & Applications

          Accessories (Primary)

          Catalogue Number Description  
          106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
          106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
          109253 Papanicolaou's solution 1a Harris' hematoxylin solution Show Pricing & Availability
          109254 Papanicolaou's solution 1b Hematoxylin solution S Show Pricing & Availability
          109271 Papanicolaou's solution 3a polychromatic solution EA 31 Show Pricing & Availability
          109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability

          Accessories (Secondary)

          Catalogue Number Description  
          106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
          106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
          109253 Papanicolaou's solution 1a Harris' hematoxylin solution Show Pricing & Availability
          109254 Papanicolaou's solution 1b Hematoxylin solution S Show Pricing & Availability
          109271 Papanicolaou's solution 3a polychromatic solution EA 31 Show Pricing & Availability
          109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability

          Related Products By: Application Facete

          Clinical Cytology
          Cytodiagnosis
          Papanicolaou

          Categories

          IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents