Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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505984
Sigma-AldrichMitochondrial Content Inducer, BRD6897 - CAS 618395-82-7 - Calbiochem
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Description
Overview
A cell-permeable indolylphenylthienopyrimidinone compound that increases mitochondrial content without affecting the cell size (~10 µM). Reduces mitochondrial protein turnover without affecting any known transcriptional programs of mitochondrial biogenesis. Reversibly increases uncoupled respiration in non-dividing cells (~50% increase in 3T3-L1 and HUVEC at 10 µM), but appears to be toxic to dividing cells. Shown to increase the expression of mitochondrial DNA encoded oxidative phosphorylation (OxPhos) genes without affecting nuclear DNA encoded OxPhos gene expression.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A cell-permeable indolylphenylthienopyrimidinone compound that increases mitochondrial content without affecting the cell size (~10 µM). Reduces mitochondrial protein turnover without affecting any known transcriptional programs of mitochondrial biogenesis. Reversibly increases uncoupled respiration in non-dividing cells (~50% increase in 3T3-L1 and HUVEC at 10 µM), but appears to be toxic to dividing cells. Shown to increase the expression of mitochondrial DNA encoded oxidative phosphorylation (OxPhos) genes without affecting nuclear DNA encoded OxPhos gene expression.
Form
Off-white powder
Intert gas (Yes/No)
Packaged under inert gas
CAS number
618395-82-7
Chemical formula
C₂₅H₂₁N₃O₂S₂
Purity
≥98% by HPLC
Solubility
DMSO (10 mg/ml)
Storage
Protect from light +2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
