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106757 Methyl 4-hydroxybenzoate

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,NF

Methyl 4-hydroxybenzoate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester

CAS #: 99-76-3 EC Number: 202-785-7 Molar Mass: 152.15 g/mol Chemical Formula: 4-(OH)C₆H₄(COOCH₃) Hill Formula: C₈H₈O₃ Grade: Ph Eur,BP,ChP,JP,NF
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106757
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Overview

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Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
99-76-3202-785-7C₈H₈O₃4-(OH)C₆H₄(COOCH₃)152.15 g/molPh Eur,BP,ChP,JP,NF

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      1.06757.9024
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          		 Double PE Sack 20 kg
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          Description
          Catalogue Number106757
          SynonymsMethylparaben, 4-Hydroxybenzoic acid methyl ester
          DescriptionMethyl 4-hydroxybenzoate
          References
          Product Information
          CAS number99-76-3
          EC number202-785-7
          GradePh Eur,BP,ChP,JP,NF
          Hill FormulaC₈H₈O₃
          Chemical formula4-(OH)C₆H₄(COOCH₃)
          Molar Mass152.15 g/mol
          HS Code2918 29 22
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.38 g/cm3 (20 °C)
          Flash point168 °C Not applicable
          Ignition temperature>600 °C
          Melting Point125 °C
          pH value5.72 (1.88 g/l, H₂O, 20 °C) (saturated solution)
          Vapor pressure<1 hPa (20 °C)
          Bulk density300 - 400 kg/m3
          Solubility1.88 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 2100 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Statement(s)H411: Toxic to aquatic life with long lasting effects.
          Precautionary Statement(s)P273: Avoid release to the environment.
          P391: Collect spillage.
          P501: Dispose of contents/ container to an approved waste disposal plant.
          RTECSDH2450000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
          Declaration (transport by air) IATA-DGRUN 3077 , 9, III
          Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
          Supplemental Information
          Specifications
          Assay (HPLC, Ph. Eur., BP, JP, NF)98.0 - 102.0 %
          Assay (HPLC, calc. on dried substance) (ChP)98.0 - 102.0 %
          Identity (IR-spectrum)passes test
          Identity (melting range)passes test
          Identity (HPLC) (ChP)passes test
          Identity (UV-spectrum)passes test
          Appearance of solution (100 g/l, Ethanol 96 %)clear and not more intense in color than reference solution BY₆
          Appearance of solution (100 g/l, ethanol 96 %) (ChP)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₁ or YG₁
          Aciditypasses test
          Melting range (lower value)≥ 125 °C
          Melting range (upper value)≤ 128 °C
          Chloride (Cl)≤ 350 ppm
          Sulfate (SO₄)≤ 240 ppm
          As (Arsenic)≤ 1 ppm
          Heavy metals (as Pb)≤ 10 ppm
          Related substances (HPLC, Ph. Eur., BP, ChP, JP, NF)passes test
          p-Hydroxy benzoic acid≤ 0.3 %
          Largest unspecified impurity≤ 0.4 %
          Sum of all impurities≤ 0.8 %
          Methanol (HS-GC)≤ 3000 ppm
          Other residual solvents (ICH Q3C)excluded by manufactoring process
          Sulfated ash (600 °C)≤ 0.1 %
          Residue on ignition (500 °C)≤ 0.1 %
          Loss on drying (room temperature, vacuum)≤ 0.5 %
          Total aerobic microbial count (TAMC)≤ 10²
          Total combined yeasts/moulds count (TYMC)≤ 10²
          Endotoxins≤ 200 I.U./g
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Not for food use.
          Corresponds to Ph Eur, BP, ChP, JP, NF.
          Global Trade Item Number
          Catalogue Number GTIN
          1.06757.5000 04022536081847
          1.06757.9024 04022536938677

          Documentation

          Material Qualification Dossier

          TitleVersion
          8.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          Methyl 4-hydroxybenzoate SDS

          Title

          Safety Data Sheet (SDS) 

          Methyl 4-hydroxybenzoate Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1.06757.5000 Fibre cartonPDF Specification Document
          1.06757.9024 Double PE SackPDF Specification Document

          Certificates

          Title