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434625 Leukotriene B₄ - CAS 71160-24-2 - Calbiochem

Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium.

Leukotriene B₄ - CAS 71160-24-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid

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434625
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
71160-24-2C₂₀H₃₂O₄

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      Description
      OverviewPotent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.
      Catalogue Number434625
      Brand Family Calbiochem®
      SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
      References
      ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
      Dokter, W.H., et al. 1994. Leukemia 8, 1181.
      Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.
      Product Information
      CAS number71160-24-2
      ATP CompetitiveN
      FormLiquid
      FormulationSupplied as oil dissolved in ethanol at 50 µg/ml.
      Hill FormulaC₂₀H₃₂O₄
      Chemical formulaC₂₀H₃₂O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPolymorphonuclear leukocytes
      Purity>97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 11

      Highly flammable.
      S PhraseS: 16-7

      Keep away from sources of ignition - No Smoking.
      Keep container tightly closed.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Flammable
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      434625-50UGCN 04055977210224

      Documentation

      Leukotriene B₄ - CAS 71160-24-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Leukotriene B₄ - CAS 71160-24-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      434625

      References

      Reference overview
      Kendall, A.P., et al. 1995. Anesthesia 50, 590.
      Dokter, W.H., et al. 1994. Leukemia 8, 1181.
      Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.

      Brochure

      Title
      Bioactive Lipids Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-December-2023 JSW
      SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
      DescriptionPotent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
      FormLiquid
      FormulationSupplied as oil dissolved in ethanol at 50 µg/ml.
      CAS number71160-24-2
      Chemical formulaC₂₀H₃₂O₄
      Structure formulaStructure formula
      Purity>97% by HPLC
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Flammable
      Merck USA index14, 5455
      ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
      Dokter, W.H., et al. 1994. Leukemia 8, 1181.
      Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.