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204910 Complement C9, Human

Complement C9, Human, CAS 80295-59-6, is a native, single-chain glycoprotein present in normal human serum at 60 µg/ml.

Complement C9, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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204910
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Overview

Replacement Information

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204910-250UGCN
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      		 Plastic ampoule 250 μg
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      Description
      OverviewNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
      Catalogue Number204910
      Brand Family Calbiochem®
      References
      ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
      Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
      Product Information
      CAS number80295-59-6
      FormLiquid
      FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
      Quality LevelMQ200
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥150,000 C9H50 units/mg
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      204910-250UGCN 04055977219890

      Documentation

      Complement C9, Human SDS

      Title

      Safety Data Sheet (SDS) 

      Complement C9, Human Certificates of Analysis

      TitleLot Number
      204910

      References

      Reference overview
      Stanley, K.K., et al. 1985. EMBO J. 4, 375.
      Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-May-2008 RFH
      DescriptionNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
      FormLiquid
      FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
      Concentration Label Please refer to vial label for lot-specific concentration
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number80295-59-6
      Purity≥95% by SDS-PAGE
      ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
      Specific activity≥150,000 C9H50 units/mg
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
      Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.