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230950 Ciglitazone - CAS 74772-77-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
74772-77-3C₁₈H₂₃NO₃S

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230950-5MGCN
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      Description
      OverviewA potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).
      Catalogue Number230950
      Brand Family Calbiochem®
      Synonyms(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I
      References
      ReferencesJha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
      Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
      Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
      Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
      Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.
      Product Information
      CAS number74772-77-3
      ATP CompetitiveN
      FormWhite to tan solid
      Hill FormulaC₁₈H₂₃NO₃S
      Chemical formulaC₁₈H₂₃NO₃S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetSelective PPARγ agonist
      Primary Target IC<sub>50</sub>EC50 = 3 µM as PPARγ agonist
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSXJ5813700
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsStock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      230950-5MGCN 04055977218312