Millipore Sigma Vibrant Logo

182540 Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem

The Aromatase Inhibitor I, also referenced under CAS 331684-05-0, controls the biological activity of Aromatase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone

Primary Target: P450 arom.
View Products on Sigmaaldrich.com
182540
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
331684-05-0C₁₇H₁₁N₃O₄

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
182540-1MGCN
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 1 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Description
      OverviewA potent, competitive, nonsteroidal inhibitor of aromatase (P450arom; IC50 = 40 nM for human aromatase). Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit 17α-hydroxylase.
      Catalogue Number182540
      Brand Family Calbiochem®
      Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
      References
      ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.
      Product Information
      CAS number331684-05-0
      ATP CompetitiveY
      FormWhite solid
      Hill FormulaC₁₇H₁₁N₃O₄
      Chemical formulaC₁₇H₁₁N₃O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetP450 arom.
      Primary Target IC<sub>50</sub>40 nM against P450arom
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      182540-1MGCN 04055977205091

      Documentation

      Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      182540

      References

      Reference overview
      Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      Synonyms4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
      DescriptionA potent, selective, nonsteroidal, competitive inhibitor of aromatase (P450arom) (IC50 = 40 nM for human aromatase) Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit human 17α-hydroxylase (P450 17) (4% inhibition at 2.5 µM).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number331684-05-0
      Chemical formulaC₁₇H₁₁N₃O₄
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesRecanatini, M., et al. 2001. J. Med. Chem. 44, 672.