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662045 Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb

This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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662045
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, M, RRbPolyclonal Antibody

Pricing & Availability

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662045-100ULCN
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      Description
      OverviewRecognizes the UCP-1 protein.
      Catalogue Number662045
      Brand Family Calbiochem®
      References
      ReferencesKozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
      Product Information
      FormLiquid
      FormulationIn PBS.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1:1000)
      Application CommentsDoes not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogena synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      662045-100ULCN 04055977261073

      Documentation

      Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb Certificates of Analysis

      TitleLot Number
      662045

      References

      Reference overview
      Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.

      Citations

      Title
    • Michael Koban and Kevin L. Swinson. (2005) Chronic REM-sleep deprivation of rats elevates metabolic rate and increases UCP1 gene expression in brown adipose tissue. American Journal of Physiology Endocrinology and Metabolism 289, E68-E74.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-August-2007 RFH
      ApplicationImmunoblotting (1:1000)
      DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
      BackgroundUncoupling protein-1 (UCP-1) is essential for the thermogenic properties of brown fat in mammals. It is inserted in the inner mitochondrial membrane by means of six α-helical hydrophobic transmembrane domains.
      HostRabbit
      Immunogen speciesMouse
      Immunogena synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
      IsotypeIgG
      Specieshuman, mouse, rat
      FormLiquid
      FormulationIn PBS.
      PreservativeNone
      CommentsDoes not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesKozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
      Citation
    • Michael Koban and Kevin L. Swinson. (2005) Chronic REM-sleep deprivation of rats elevates metabolic rate and increases UCP1 gene expression in brown adipose tissue. American Journal of Physiology Endocrinology and Metabolism 289, E68-E74.
      		•