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AB10343 Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7)

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AB10343
50 µL  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB10343
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7)
      Alternate Names
      • 3,4-catechol estrogen specific
      • UDP glucuronosyltransferase 2 family, polypeptide B7
      • UDP glycosyltransferase 2 family, polypeptide B7
      • UDP-glucuronosyltransferase 2B7
      • UDP-glucuronyltransferase, family 2, beta-7
      Background InformationUGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme active in the liver, kidneys, gastrointestinal tract and brain.It is found on the endoplasmic reticulum and nuclear membranes of cells. UGT2B7 is the major isoform for the metabolism of morphine to the main metabolites.
      Product Information
      FormatSerum
      PresentationRaw rabbit serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect UGT2B7 (UDP-Glycosyltransferase 2B family) using this Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7) validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant human UGT2B7 protein.
      Biological Information
      ImmunogenRecombinant human UGT2B7
      Epitopea.a S80–V122
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.[supplied by OMIM]
      Gene Symbol
      • EC 2.4.1.17
      • UDPGT
      • UDPGTh-2
      • UGT2B9
      • UGTB2B9
      UniProt Number
      Molecular Weight61 kDa
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by Western Blot on baculovirus expressed recombinant human UGT2B7 protein.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
      Packaging Information
      Material Size50 µL
      Global Trade Item Number
      Catalogue Number GTIN
      AB10343 04053252362729