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ABC832 Anti-TMEM16B Antibody

Anti-TMEM16B Antibody is an antibody against TMEM16B for use in western blotting, IHC & immunofluorescence.

Anti-TMEM16B Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ANO2, TMEM16B UniProt Number: Q9NQ90
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ABC832
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC832
      DescriptionAnti-TMEM16B Antibody
      Alternate Names
      • Anoctamin-2
      • Transmembrane protein 16B
      Background InformationAnoctamin-2, also known as Transmembrane protein 16B (TMEM16B) are subunits of Calcium-activated chloride channels (CaCC) which mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TMEM16B Antibody is an antibody against TMEM16B for use in western blotting, IHC & immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 5 μg/mL from a representative lot detected TMEM16B in human brain tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TMEM16B in human brain cells.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the N-terminus of human TMEM16B.
      EpitopeN-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody will not cross-react with TMEM16A.
      Species Reactivity
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ANO2
      • TMEM16B
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~128 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue.

      Western Blotting Analysis: 2 μg/mL of this antibody detected TMEM16B in rat brain tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC832 04053252943904

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies