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MABC1109 Anti-Mucin-9 Antibody, clone 7E10

Anti-Mucin-9, clone 7E10, Cat. No. MABC1109, is mouse monoclonal antibody that detects Mucin-9 (Oviductin) and has been tested for use in ELISA, Immunohistochemistry (Paraffin), and Western Blotting.

Anti-Mucin-9 Antibody, clone 7E10 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Gene Symbol: OVGP1, MUC9, OGP UniProt Number: Q12889
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MABC1109
100 μg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, IH(P), WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC1109
      DescriptionAnti-Mucin-9 Antibody, clone 7E10
      Alternate Names
      • Oviduct-specific glycoprotein
      • Estrogen-dependent oviduct protein
      • Oviductal glycoprotein
      • Oviductin
      Background InformationOviduct-specific glycoprotein (UniProt: Q12889; also known as Estrogen-dependent oviduct protein, Mucin-9, Muc-9, Oviductal glycoprotein, Oviductin) is encoded by the OVGP1 (also known as MUC9, OGP) gene (Gene ID: 5016) in human. The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats. Mucin-9 belongs to the glycosyl hydrolase 18 family that plays a key role in sperm capacitation, fertilization, and development of early embryos. It is secreted from non-ciliated oviductal epithelial cells and its expression is highest at the time of ovulation. Mucin-9 is synthesized with a 21 amino acid signal peptide that is subsequently cleaved off to generate mature protein. Mucin-9 is an estrogen-dependent protein that is secreted into the lumen of the oviduct and associates with the zona pellucida of postovulatory oocytes in oviductal transit, but is absent in ovarian oocytes.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Mucin-9, clone 7E10, Cat. No. MABC1109, is mouse monoclonal antibody that detects Mucin-9 (Oviductin) and has been tested for use in ELISA, Immunohistochemistry (Paraffin), and Western Blotting.
      Key Applications
      • ELISA
      • Immunohistochemistry (Paraffin)
      • Western Blotting
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Mucin-9 in human placenta tissue.

      Western Blotting Analysis: A representative lot detected Mucin-9 in Western Blotting applications (Maines-Bandiera, S., et. al. (2010). Int J Gynecol Cancer. 20(1):16-22).

      ELISA Analysis: A representative lot detected Mucin-9 in ELISA applications (Maines-Bandiera, S., et. al. (2010). Int J Gynecol Cancer. 20(1):16-22).

      Immunohistochemistry Analysis: A representative lot detected Mucin-9 in Immunohistochemistry applications (Maines-Bandiera, S., et. al. (2010). Int J Gynecol Cancer. 20(1):16-22).
      Biological Information
      ImmunogenA mixture of GST-tagged recombinant fragments corresponding to 81 amino acids from the N-terminal half and 112 amino acids from the C-terminal region of human Mucin-9/Oviductin.
      Clone7E10
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone 7E10 detects Mucin-9 (Oviductin) in human oviduct sections.
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Species Reactivity NoteHuman.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • OVGP1
      • MUC9
      • OGP
      Purification MethodProtein G purified
      UniProt Number
      Molecular Weight75.42 kDa calculated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human oviduct tissue.

      Immunohistochemistry Analysis: A 1:250 dilution of this antibody detected Mucin-9 in human oviduct tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC1109 04054839328817