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AB1745 Anti-Connexin 45 Antibody, near CT, cytoplasmic

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AB1745
100 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RIP, WB, IHCRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB1745
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Connexin 45 Antibody, near CT, cytoplasmic
      Alternate Names
      • Cx45
      Product Information
      FormatPurified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Connexin 45 using this Anti-Connexin 45 Antibody, near C-terminus, cytoplasmic validated for use in IP, WB, IH.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunohistochemistry
      Application NotesOptimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenKLH-conjugated synthetic, linear peptide corresponding to human Connexin 45 near the C-terminus.
      Epitopenear C-terminus, cytoplasmic
      HostRabbit
      SpecificityRecognizes Human, rat and mouse Connexin 45. Due to sequence homologies, this antibody is also expected to react with canine (100% homology) Connexin 45. Other species not tested.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NotePredicted to react with dog based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • ENSG00000182963
      • Cx45
      • Connexin-45
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P36383 # One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      SIZE: 396 amino acids; 45483 Da
      SUBUNIT: A connexon is composed of a hexamer of connexins.
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
      SIMILARITY: SwissProt: P36383 ## Belongs to the connexin family. Alpha-type (group II) subfamily.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      AB1745 04053252582196