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MABD122A4 Anti-CD73, clone AA60-E3-3, Alexa Fluor® 488 conjugate Antibody

This Anti-CD73, clone AA60-E3-3 is validated for use in Immunocytochemistry for the detection of CD73.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Mesenchymal Stem Cells Gene Symbol: NT5E, NT5, NTE UniProt Number: Q61503
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MABD122A4
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HICCMAlexaFluor®488Monoclonal Antibody
      Description
      Catalogue NumberMABD122A4
      DescriptionAnti-CD73, clone AA60-E3-3, Alexa Fluor® 488 conjugate Antibody
      Alternate Names
      • CD-73
      • 5'-nucleotidase
      • 5'-NT
      • ecto-5'-nucleotidase
      Background InformationCD73, also known as Ecto-5'-nucleotidase, catalyzes the conversion of purine 5' mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations.
      Product Information
      FormatAlexaFluor®488
      PresentationPurified mouse monoclonal IgG1κ conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-CD73, clone AA60-E3-3 is validated for use in Immunocytochemistry for the detection of CD73.
      Key Applications
      • Immunocytochemistry
      Application NotesEvaluated by Immunocytochemistry on human bone marrow mesenchymal stem cells. Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.
      Biological Information
      ImmunogenWhole Mouse Dermal Lymphatic Endothelial Cells (DLEC)
      CloneAA60-E3-3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with human. Predicted to work in mouse based on immunogen design.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NT5E
      • NT5
      • NTE
      Purification MethodProtein G Purified
      UniProt Number
      Molecular WeightThe unconjugated parent antibody (Catalog No. MABD122) has an observed MW at 63 kDA.
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry on human adipose mesenchymal stem cells.
      Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      MABD122A4 04053252978814