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ABD134 Anti-BMP Antibody15

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ABD134
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABD134
      DescriptionAnti-BMP Antibody15
      Alternate Names
      • Bone morphogenetic protein 15
      • BMP-15
      • Growth/differentiation factor 9B
      • GDF9B
      • GDF-9B
      • ODG2
      • POF4
      Background InformationBone morphogenetic protein 15 (BMP15), also known as Growth/differentiation factor 9B (GDF9B), is part of the transforming growth factor-beta (TGF-β) superfamily. BMP15 is an oocyte-specific growth and differentiation factor that stimulates folliculogenesis and development as well as granulosa cell (GC) growth. BMP15 is expressed exclusively in the oocyte. BMP15 defects are linked to ovarian dysgenesis type 2 (ODG2) and premature ovarian failure type 4 (POF4). Potentially, BMP15 could be an oogenesis marker, used to monitor the differentiation of human amniotic fluid stem cells into oocyte-like cells.
      References
      Product Information
      FormatAffinity Purified
      Control
      • NIH/3T3 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-BMP Antibody15 is a highly specific rabbit polyclonal antibody, that targets BMP & has been tested in western blotting & ICC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected BMP15 in NIH/3T3 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human BMP15.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • BMP15
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~53 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in NIH/3T3 cell lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected BMP15 in 15 µg of NIH/3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABD134 04053252906954