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176002 Anti-Angiopoietin-2 Rabbit pAb

Anti-Angiopoietin-2, rabbit polyclonal, recognizes the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein. It is validated for ELISA, WB, IF, and IHC.

Anti-Angiopoietin-2 Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Ang-2

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176002
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
MRbPolyclonal Antibody

Pricing & Availability

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176002-50UGCN
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      		 Plastic ampoule 50 μg
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      Description
      OverviewRecognizes both the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein in cell culture medium. Does not cross-react with Ang-1.
    • Antibody Target Gene Symbol: ANGPT2
    • Target Synonym: AGPT2, ANG II, ANG-2, ANGIOPOIETIN, ANGIOPOIETIN 2, Angiotensin 2, Angrp
    • Entrez Gene Name: angiopoietin 2
    • Hu Entrez ID: 285
    • Mu Entrez ID: 11601
    • Rat Entrez ID: 89805
      		•
      Catalogue Number176002
      Brand Family Calbiochem®
      SynonymsAnti-Ang-2
      References
      ReferencesMaisonpierre, P.C., et al. 1997. Science 277, 55.
      Davis, S., et al. 1996. Cell 87, 1161.
      Suri, S. et al. 1996. Cell 87, 1171.
      Product Information
      FormLiquid
      FormulationIn PBS, 0.1% BSA, pH 7.5.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Immunoblotting (Western Blotting)
      Immunofluorescence
      Immunohistochemistry
      Application NotesELISA (0.1-1 µg/ml)
      Immunoblotting (1-10 µg/ml)
      Immunofluorescence (2-20 µg/ml)
      Immunohistochemistry (2-20 µg/ml)
      Application CommentsThe immunogenic peptide sequence is 71% (15/21 amino acids) conserved in the human angiopoietin-2 protein. Does not cross-react with angiopoietin-1. Variables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogena synthetic peptide corresponding to a 21 amino acid cytoplasmic sequence at the N-terminus of mouse angiopoietin-2
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      176002-50UGCN 04055977222944

      Documentation

      Anti-Angiopoietin-2 Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Angiopoietin-2 Rabbit pAb Certificates of Analysis

      TitleLot Number
      176002

      References

      Reference overview
      Maisonpierre, P.C., et al. 1997. Science 277, 55.
      Davis, S., et al. 1996. Cell 87, 1161.
      Suri, S. et al. 1996. Cell 87, 1171.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-May-2008 JSW
      SynonymsAnti-Ang-2
      ApplicationELISA (0.1-1 µg/ml)
      Immunoblotting (1-10 µg/ml)
      Immunofluorescence (2-20 µg/ml)
      Immunohistochemistry (2-20 µg/ml)
      DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognizes both the ~55 kDa nonglycosylated and the ~70 kDa glycosylated forms of angiopoietin-2.
      BackgroundAngiopoietin (Ang-2) is a recently identified secreted protein that may act as an antagonist for Ang-1 and Tie-2. Ang-1 and Ang-2 have ~60% sequence homology. Ang-2 expression is abundant in the dorsal aorta and major aortic branches. Ang-2 transcripts in fetal liver are restricted to cells at the lumen of hepatic vessels. In adults, Ang-2 is prominently expressed in tissues that may undergo vascular remodeling (ovary, placenta, and uterus).
      HostRabbit
      Immunogen speciesMouse
      Immunogena synthetic peptide corresponding to a 21 amino acid cytoplasmic sequence at the N-terminus of mouse angiopoietin-2
      IsotypeIgG
      Speciesmouse
      FormLiquid
      FormulationIn PBS, 0.1% BSA, pH 7.5.
      Concentration Label Please refer to vial label for lot-specific concentration
      PreservativeNone
      CommentsThe immunogenic peptide sequence is 71% (15/21 amino acids) conserved in the human angiopoietin-2 protein. Does not cross-react with angiopoietin-1. Variables associated with assay conditions will dictate the optimal working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesMaisonpierre, P.C., et al. 1997. Science 277, 55.
      Davis, S., et al. 1996. Cell 87, 1161.
      Suri, S. et al. 1996. Cell 87, 1171.