531535 Sigma-AldrichAP-1/NF-κB Dual Inhibitor, SP100030 - CAS 154563-54-9 - Calbiochem
A cell-permeable, potent, reversible T-cell specific inhibitor of both AP-1 and NF-κB transcriptional activation (IC₅₀ = 50 nM)
More>> A cell-permeable, potent, reversible T-cell specific inhibitor of both AP-1 and NF-κB transcriptional activation (IC₅₀ = 50 nM) Less<<Synonyms: 2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3ʹ,5ʹ-bis(trifluoromethyl)phenyl)-carboxamide, N-(3,5-bis(Trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide, Activator Protein-1 Activation Inhibitor; AP-1 Activation Inhibitor, NF-κB Activation Inhibitor XI, SP-100030, Nuclear Factor-κB Activation Inhibitor XI
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Overview
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Key Spec Table
CAS # | Empirical Formula |
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154563-54-9 | C₁₄H₅ClF₉N₃O |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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5.31535.0001CN |
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Glass bottle | 10 mg |
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Product Information | |
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CAS number | 154563-54-9 |
Form | Off-white solid |
Hill Formula | C₁₄H₅ClF₉N₃O |
Chemical formula | C₁₄H₅ClF₉N₃O |
Reversible | Y |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | AP-1 and NF-κB |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
5.31535.0001CN | 04055977260359 |
Documentation
AP-1/NF-κB Dual Inhibitor, SP100030 - CAS 154563-54-9 - Calbiochem SDS
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References
Reference overview |
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Ye, N., et al. 2014. J. Med. Chem. 57, 6930. Moore-Carrasco, R., et al. 2009. Anticancer Res. 29, 1315. Huang, T.J., et al. 2001. Br. J. Pharmacol. 134, 1029. Gerlag, D.M., et al. 2000. J. Immunol. 165,1652. Sullivan, R.W., et al. 1998. J. Med. Chem. 41, 413. Goldman, M.E., et al. 1996. Transplant. Proc. 28, 3106. |
Brochure
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NPI Flyer- Epigenetics and Nuclear Function Feature |
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Technical Info
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White Paper: Further considerations of antibody validation and usage. |
Data Sheet | ||||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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