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103132 1,4-Dioxane

1,4-Dioxane for liquid chromatography LiChrosolv®. CAS 123-91-1, pH 6 - 8 (500 g/l, H₂O, 20 °C).

1,4-Dioxane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Glycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane

CAS #: 123-91-1 EC Number: 204-661-8 Molar Mass: 88.11 g/mol Hill Formula: C₄H₈O₂
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103132
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar Mass
123-91-1204-661-8C₄H₈O₂88.11 g/mol

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      1.03132.2500
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          Description
          Catalogue Number103132
          SynonymsGlycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane
          OverviewWith their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.
          References
          Product Information
          CAS number123-91-1
          EC index number603-024-00-5
          EC number204-661-8
          Hill FormulaC₄H₈O₂
          Molar Mass88.11 g/mol
          HS Code2932 99 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Application1,4-Dioxane for liquid chromatography LiChrosolv®. CAS 123-91-1, pH 6 - 8 (500 g/l, H₂O, 20 °C).
          Biological Information
          Physicochemical Information
          Boiling point101.5 °C (1013 hPa)
          Density1.034 g/cm3 (20 °C)
          Explosion limit1.7 - 25.2 %(V)
          Flash point11 °C
          Ignition temperature300 °C
          Melting Point11.8 °C
          pH value6.0 - 8 (500 g/l, H₂O, 20 °C)
          Vapor pressure36 hPa (20 °C)
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 5200 mg/kg
          LD 50 dermalLD50 Rabbit 7600 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H225: Highly flammable liquid and vapour.
          H319: Causes serious eye irritation.
          H335: May cause respiratory irritation.
          H350: May cause cancer.
          EUH019: May form explosive peroxides.
          EUH066: Repeated exposure may cause skin dryness or cracking.
          Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
          P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
          P233: Keep container tightly closed.
          P240: Ground and bond container and receiving equipment.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P308 + P313: IF exposed or concerned: Get medical advice/ attention.
          P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
          Signal WordDanger
          RTECSJG8225000
          Storage class3 Flammable liquids
          WGKWGK 3 highly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Categories of dangerhighly flammable, irritant, carcinogenic
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 1165 , 3, II
          Declaration (transport by air) IATA-DGRUN 1165 , 3, II
          Declaration (transport by sea) IMDG-CodeUN 1165 , 3, II
          Supplemental Information
          Specifications
          Purity (GC)≥ 99.8 %
          Identity (IR)conforms
          Evaporation residue≤ 2.0 mg/l
          Water≤ 0.02 %
          Acidity≤ 0.0002 meq/g
          Alkalinity≤ 0.0002 meq/g
          Transmission (at 245 nm)≥ 50 %
          Transmission (at 270 nm)≥ 80 %
          Transmission (from 300 nm)≥ 98 %
          Filtered by 0.2 µm filter
          Global Trade Item Number
          Catalogue Number GTIN
          1.03132.1000 04022536040158
          1.03132.2500 04022536040165

          Documentation

          1,4-Dioxane SDS

          Title

          Safety Data Sheet (SDS) 

          1,4-Dioxane Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1.03132.1000 Glass bottlePDF Specification Document
          1.03132.2500 Glass bottlePDF Specification Document

          Technical Info

          Title
          Pharmaceutical impurity profiling Application guide
          Polar Hydrophilic Compounds in Pharmaceutical Analysis - SeQuant®ZIC®-HILIC HPLC for control of active ingredients, impurities, counterions and excipients.

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