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575003 α-Synuclein A53T, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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575003
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Overview

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575003-200UGCN
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      		 Plastic ampoule 200 μg
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      Description
      OverviewRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. A point mutant (A53T) of α-synuclein gene that has been linked to autosomal dominant early-onset Parkinson’s disease (PD).
      Catalogue Number575003
      Brand Family Calbiochem®
      References
      ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
      Park, S.M., et al. 2002. Blood 100, 2506.
      Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
      Product Information
      FormLiquid
      FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      575003-200UGCN 04055977189209

      Documentation

      α-Synuclein A53T, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      α-Synuclein A53T, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      575003

      References

      Reference overview
      Lashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
      Park, S.M., et al. 2002. Blood 100, 2506.
      Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      DescriptionRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson's Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.
      FormLiquid
      FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥95% by SDS-PAGE
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
      Park, S.M., et al. 2002. Blood 100, 2506.
      Polymeropoulos, M.H., et al. 1997. Science 276, 2045.