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Choose Customizable Panels & Premixed Kits - OR - Cell Signaling MAPmates™

Design and price your MILLIPLEX® MAP kits.

Customizable Panels & Premixed Kits

Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.

Cell Signaling Kits & MAPmates™

Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.

Select Available MAPmates™
Select Premixed Panels

The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr

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Select A Sample Type	For some panels, sample type will determine which analytes can be plexed together.

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Design your own kit or select from our premixed and single plex panels.

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Custom Premix
Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.

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Qty	Catalogue Number	Ordering Description	Qty/Pack	List Price
			96-Well Plate

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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)

Qty	Catalogue Number	Ordering Description	Qty/Pack	List Price
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

Space Saver Option
Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.

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Featured Antibody
Anti-phospho-TrkA (Tyr794) Antibody Cultured primary rat basal forebrain neurons were stimulated by the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) for TrkA transactivation prior to immunofluorescent analysis using Anti-phospho-TrkA (Tyr794) (Cat. No. ABN1383, green). Image courtesy of Dr. Moses V. Chao, Langone Medical Center, New York University.

Brain development, including mature wiring related to memory and learning, is partly regulated by extracellular signaling molecules. A group of these molecules called neurotrophins regulate the apoptosis, survival and differentiation of selective populations of neurons during embryonic development. Neurotrophins also regulate maintenance of specific functions in adulthood. Neuronal activity regulates neurotrophin production, and, in turn, neurotrophins have a potent effect on the target neuron’s signaling.

The neurotrophin family members include Nerve Growth Factor (NGF), Brain Derived Neurotrophic Factor (BDNF), Neurotrophin-3 (NT3) and Neurotrophin- 4/5 (NT4/5). These neurotrophins support different neuronal populations within the central and peripheral nervous systems. The trophic (survival promoting) and tropic (directing neurite outgrowth) properties of neurotrophins demonstrate their potential for the treatment of neurodegenerative diseases and peripheral neuropathies.

Merck provides a wide selection of antibodies and related products that will assist in the study of neurotrophic factors and their effects.

Products involving Neurotrophic Factors

	Antibodies	ELISAs & Assays	Proteins	Sample Packs / Kits
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CNTF
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NGF
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