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324355 n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem

CAS 69227-93-6 is a non-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
324355
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Overview

Replacement Information

Key Spec Table

CAS #
69227-93-6

Products

Catalogue NumberPackaging Qty/Pack
324355-100GM Glass bottle 100 gm
324355-1GM Glass bottle 1 gm
324355-250GM Glass bottle 250 gm
324355-25GM Glass bottle 25 gm
324355-5GM Plastic ampoule 5 gm
Description
OverviewNon-ionic detergent similar to n-octyl-β-D-glucopyranoside; however, increased alkyl chain length has been shown to increase thermal stability of lipid-free rhodopsin in solution. Useful in membrane-protein solubilization studies. Aggregation number: 98.
Absorbance (10%, H2O, 260 nm): <1.0.
Catalogue Number324355
Brand Family Calbiochem®
References
ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
Rosevear, P., et al. 1980. Biochemistry 19, 4108.
Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
Product Information
CAS number69227-93-6
Aggregation Number98
CMC100-600 µM
FormWhite solid
Hygroscopic Hygroscopic
Micellar weight50000
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Contaminantsdodecanol 1H NMR: ≤1%
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C).
Stock solutions are stable for up to 3 months at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324355-100GM 04055977216417
324355-1GM 07790788054175
324355-250GM 04055977216431
324355-25GM 04055977216424
324355-5GM 04055977216448

Documentation

n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

n-Dodecyl-β-D-maltoside, ULTROL® Grade - CAS 69227-93-6 - Calbiochem Certificates of Analysis

TitleLot Number
324355

References

Reference overview
Witzmann, F., et al. 1991. Electrophoresis 12, 687.
Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
Rosevear, P., et al. 1980. Biochemistry 19, 4108.
Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.

Brochure

Title
Biological Detergents Brochure
CALBIOSORBﾙ Technical Bulletin

Citations

Title
  • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision20-December-2010 JSW
    DescriptionA water-soluble nonionic detergent. Studies on rhodopsin have shown that alkyl glycosides with longer alkyl chains are better at preserving the protein's properties. In addition, dodecyl maltoside's longer hydrophilic group confers higher solubility in water. This is in contrast to undecyl and dodecyl glucosides, which have low solubility in water. Due to its low CMC, dodecyl maltoside is not easily removed by dialysis. The half time for dialysis is 20 h. This detergent is milder than nonyl glucoside. Of several glycosides tested, dodecyl maltoside was found to be the most useful for the preparation of active cytochrome oxidase from Neurospora. In octyl glucoside, cytochrome oxidase dissociated into its subunits and became inactive. Similarly, beef heart oxidase when equilibrated in octyl glucoside formed a mixture of polymer, dimer, and lower molecular weight forms and underwent denaturation. In contrast, the enzyme, when equilibrated in dodecyl maltoside, was found to exist as a uniform species of 30 kDa, which is consistent with an active dimeric form. Dodecyl maltoside has a critical micelle concentration (CMC) of 100-600 µM and a micellar weight of 70,000. Aggregation number: 98.
    FormWhite solid
    CAS number69227-93-6
    Structure formulaStructure formula
    Purity≥98% by HPLC
    Contaminantsdodecanol 1H NMR: ≤1%
    SolubilityH₂O (100 mg/ml)
    Storage +2°C to +8°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, refrigerate (4°C).
    Stock solutions are stable for up to 3 months at 4°C.
    Toxicity Standard Handling
    ReferencesWitzmann, F., et al. 1991. Electrophoresis 12, 687.
    Bass, W.T., and Bricker, T.M. 1988. Anal. Biochem. 171, 330.
    Rosevear, P., et al. 1980. Biochemistry 19, 4108.
    Grip, W.J., and Bovee-Geurts, P.H.M. 1979. Chem. Phys. Lipids 23, 321.
    Stubbs, G.W., et al. 1976. Biochim. Biophys. Acta 425, 46.
    Citation
  • Serban P. Georgescu, et al. (2005) Modulator recognition factor 1 (MRF1), an ARID-family member, is a novel co-repressor for estrogen receptor α. Molecular Endocrinology 19, 2491-2501.
    		•