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654380 Tunicamycin, Streptomyces lysosuperficus - CAS 11089-65-9 - Calbiochem

654380
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Overview

Key Spec Table

CAS #Empirical Formula
11089-65-9C₃₉H₆₄N₄O₁₆

Products

Catalogue NumberPackaging Qty/Pack
654380-10MG Glass bottle 10 mg
654380-50MG Alu drum 50 mg
Description
OverviewA nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570).
Catalogue Number654380
Brand Family Calbiochem®
References
ReferencesTordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857.
Price, B.D., et al. 1992. J. Cell Physiol. 152, 545.
Product Information
CAS number11089-65-9
FormWhite to off-white solid
Hill FormulaC₃₉H₆₄N₄O₁₆
Chemical formulaC₃₉H₆₄N₄O₁₆
ReconstitutionAqueous solutions can be prepared from stock solutions in DMSO by diluting with H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
Structure formula ImageStructure formula Image
Quality LevelMQ200
Biological Information
Primary TargetN-linked glycosylation
Secondary targetthrombin-induced Ca2+ mobilization in cells
Purity≥98% by HPLC (A+B+C+D)
Safety Information according to GHS
RTECSYO7980200
Safety Information
R PhraseR: 26/27/28-60-61

Very toxic by inhalation, in contact with skin and if swallowed.
May impair fertility.
May cause harm to the unborn child.
S PhraseS: 22-36/37/39-45

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
Global Trade Item Number
Catalogue Number GTIN
654380-10MG 04055977184686
654380-50MG 04055977184693