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654380
Sigma-AldrichTunicamycin, Streptomyceslysosuperficus - CAS 11089-65-9 - Calbiochem
This product can no longer be ordered through emdmillipore.com. Please refer to (Cat. No. 654380) on sigmaaldrich.com.
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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570).
Catalogue Number
654380
Brand Family
Calbiochem®
References
References
Tordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857. Price, B.D., et al. 1992. J. Cell Physiol.152, 545.
Product Information
CAS number
11089-65-9
Form
White to off-white solid
Hill Formula
C₃₉H₆₄N₄O₁₆
Chemical formula
C₃₉H₆₄N₄O₁₆
Reconstitution
Aqueous solutions can be prepared from stock solutions in DMSO by diluting with H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
Very toxic by inhalation, in contact with skin and if swallowed. May impair fertility. May cause harm to the unborn child.
S Phrase
S: 22-36/37/39-45
Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+15°C to +30°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
Global Trade Item Number
Catalogue Number
GTIN
654380-10MG
04055977184686
654380-50MG
04055977184693
Documentation
Tunicamycin, Streptomyceslysosuperficus - CAS 11089-65-9 - Calbiochem SDS
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
19-September-2007 RFH
Description
A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells.
Form
White to off-white solid
CAS number
11089-65-9
RTECS
YO7980200
Chemical formula
C₃₉H₆₄N₄O₁₆
Structure formula
Purity
≥98% by HPLC (A+B+C+D)
Solubility
DMSO (10 mg/ml), DMF, or Pyridine. Aqueous solutions can be prepared from DMSO stock solutions by diluting in H₂O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0.
Storage
+15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
Toxicity
Highly Toxic & Carcinogenic / Teratogenic
Merck USA index
14, 9819
References
Tordai, A., et al. 1995. Biochem. Biophys. Res. Commun. 206, 857. Price, B.D., et al. 1992. J. Cell Physiol.152, 545.