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100002 Tri-n-butyl phosphate

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
126-73-8204-800-2C₁₂H₂₇O₄P(C₄H₉O)₃PO266.31 g/molPh Eur

Products

Catalogue NumberPackaging Qty/Pack
1000020500 Glass bottle 500 ml
1000022500 Glass bottle 2.5 l
1000029026 Drum stainl. st. 25 l
Description
Catalogue Number100002
SynonymsTBP
DescriptionTri-n-butyl phosphate
References
Product Information
CAS number126-73-8
EC index number015-014-00-2
EC number204-800-2
GradePh Eur
Hill FormulaC₁₂H₂₇O₄P
Chemical formula(C₄H₉O)₃PO
Molar Mass266.31 g/mol
HS Code2919 90 00
Structure formula ImageStructure formula Image
Applications
Biological Information
Physicochemical Information
Boiling point289 °C (1013 hPa) (decomposition)
Density0.977 g/cm3 (20 °C)
Evaporation number<0.001
Flash point145 °C
Ignition temperature400 °C
Melting Point-79 °C
Vapor pressure36 hPa (178 °C)
Solubility6 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 1550 mg/kg
LD 50 dermalLD50 Rabbit > 3100 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H302: Harmful if swallowed.
H315: Causes skin irritation.
H351: Suspected of causing cancer.
H412: Harmful to aquatic life with long lasting effects.
Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
P264: Wash skin thoroughly after handling.
P273: Avoid release to the environment.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
Signal WordWarning
RTECSTC7700000
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerharmful, irritant, carcinogenic
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Purity (GC)≥ 99 %
Identity (IR-spectrum)passes test
Appearancepasses test
Aciditypasses test
Chloride (Cl)≤ 200 ppm
n-Butyl alcohol (GC)≤ 1000 ppm
Other residual solvents (ICH Q3C)excluded by manufacturing process
Related substances (Highest single impurity)≤ 0.1 %
Related substances (Sum of all impurities)≤ 0.3 %
Water (according to Karl Fischer)≤ 0.1 %
Total aerobic microbial count (TAMC)≤ 1000 CFU/ml
Total combined yeasts/moulds count (TYMC)≤ 100 CFU/ml
Bacterial endotoxins
≤ 10 I.U./ml
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur
≤ 10 I.U./ml
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur
Global Trade Item Number
Catalogue Number GTIN
1000020500 04027269080457
1000022500 04027269080464
1000029026 04027269080471

Documentation

Material Qualification Dossier

TitleVersion
8.0

Quality Management Dossier (Open Access)

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Quality Management Dossier

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Operational Excellence Dossier

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Tri-n-butyl phosphate SDS

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Safety Data Sheet (SDS) 

Tri-n-butyl phosphate Certificates of Analysis

Product Number PackagingSpecificationLot Number
1000020500 Glass bottlePDF Specification Document
1000022500 Glass bottlePDF Specification Document
1000029026 Drum stainl. st.PDF Specification Document

Certificates

Title