472804 Sigma-AldrichS-Methyl-L-thiocitrulline, Dihydrochloride - CAS 209589-59-3 - Calbiochem
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.
More>> A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC₅₀ = 300 nM) compared to the endothelial enzyme (IC₅₀ = 5.4 µM). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Nδ-(S-Methyl)isothioureido-L-ornithine
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Overview
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 209589-59-3 | C₇H₁₅N₃O₂S · 2HCl |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 472804-10MG | Plastic ampoule | 10 mg |
| References | |
|---|---|
| References | Krishnaswamy, N., et al. 1995. J. Biol. Chem. 270, 11103. Furfine, E.S., et al. 1994. J. Biol. Chem. 269, 26677. Narayanan, K., and Griffith, O.W. 1994. J. Med. Chem. 37, 885. |
| Product Information | |
|---|---|
| CAS number | 209589-59-3 |
| ATP Competitive | N |
| Form | White to off-white solid |
| Hill Formula | C₇H₁₅N₃O₂S · 2HCl |
| Chemical formula | C₇H₁₅N₃O₂S · 2HCl |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Rat neuronal nitric oxide synthase |
| Primary Target IC<sub>50</sub> | 300 nM for rat neuronal nitric oxide synthase |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Standard Handling |
| Storage | +2°C to +8°C |
| Hygroscopic | Hygroscopic |
| Do not freeze | Ok to freeze |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 472804-10MG | 04055977185331 |