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528208 Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem

528208
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Overview

Products

Catalogue NumberPackaging Qty/Pack
528208-50UG Plastic ampoule 50 μg
Description
OverviewHighly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t½ = 145 hours at 37°C, pH 7.4). Inhibits uPA (Ki = 5.1 x 106 M-1 sec-1) and tPA (Ki = 7.9 x 105 M-1 sec-1).
Catalogue Number528208
Brand Family Calbiochem®
SynonymsPAI-1, Mutant
References
ReferencesBerkenpas, M.B., et al. 1995. EMBO J. 14, 2969.
Product Information
ATP CompetitiveN
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetPlasminogen Activator
Primary Target K<sub>i</sub>5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively
Purity≥95% by SDS-PAGE assay
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Catalogue Number GTIN
528208-50UG 04055977196498