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FCMAB170F Milli-Mark Anti-CD4 -FITC Antibody, clone MT310

FCMAB170F
100 tests  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMFITCMonoclonal Antibody
Description
Catalogue NumberFCMAB170F
Trade Name
  • Milli-Mark
DescriptionMilli-Mark Anti-CD4 -FITC Antibody, clone MT310
Alternate Names
  • T-cell surface antigen T4/Leu-3
Background InformationCD4 is a 55 kDa glycoprotein with four immunoglobulin-like external domains, a transmembrane domain and a highly conserved intracellular domain (Leong, 1999). CD4 acts as a coreceptor in MHC class II-restricted antigen-induced T-cell activation. Further, CD4 has a role in the regulation of T-B lymphocyte adhesion in the absence of antigen recognition, and in thymic differentiation (Piatier-Tonneau, 2002). CD4 is expressed on thymocyte subsets, it marks helper/inducer T cells, and it is expressed in 55-65% of mature peripheral T cells. Subpopulations of suppressor or cytotoxic T cells can be identified among CD4-positive T cells. CD4 is also expressed on monocytes/macrophages, Langerhans cells and other dendritic cells. CD4 is not expressed on B cells. Anti-CD4, MT310, was included in the Second International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with the CD4 antigen (Miedema, 1986).
References
Product Information
FormatFITC
HS Code3002 15 90
Control
  • Human Lymphocytes
PresentationPurified Mouse monoclonal IgG1 kappa conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-CD4 -FITC Antibody, clone MT310 is an antibody against CD4 for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
CloneMT310
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD4 antigen.
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 55 kDa (Leong, 1999)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using human lymphocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCMAB170F 04053252746260

Documentation

Milli-Mark Anti-CD4 -FITC Antibody, clone MT310 SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark Anti-CD4 -FITC Antibody, clone MT310 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD4 -FITC, clone MT310 - 2141848 2141848
Milli-Mark Anti-CD4 -FITC, clone MT310 - 2145103 2145103
Milli-Mark Anti-CD4 -FITC, clone MT310 - NRG1762712 NRG1762712
Milli-Mark Anti-CD4 -FITC, clone MT310 - 2266750 2266750
Milli-Mark™ Anti-CD4 -FITC -2514237 2514237
Milli-Mark™ Anti-CD4 -FITC, -2676645 2676645
Milli-Mark™ Anti-CD4 -FITC, clone MT310 2487756
Milli-Mark™ Anti-CD4 -FITC, clone MT310 - 3614132 3614132
Milli-Mark™ Anti-CD4 -FITC, clone MT310 Conjugate 3052524
Milli-Mark™ Anti-CD4 -FITC,clone MT310 -2681326 2681326

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Life Science Research > Antibodies and Assays > Primary Antibodies