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FCMAB185AP Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37

FCMAB185AP
100 tests  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMAPCMonoclonal Antibody
Description
Catalogue NumberFCMAB185AP
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD19 -APC Antibody, clone HD37
Alternate Names
  • Differentiation antigen CD19
    B-lymphocyte surface antigen B4
    T-cell surface antigen Leu-12
  • B-lymphocyte antigen CD19
Background InformationCD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).
References
Product Information
FormatAPC
Control
  • Human Lymphocytes
PresentationPurified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
Quality LevelMQ100
Applications
ApplicationThis Milli-Mark Anti-CD19 -APC Antibody, clone HD37 is validated for use in FC for the detection of CD19 -APC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenHairy cell leukemia cells
CloneHD37
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD19 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight120 kDa (Pezzutto, 1987; Sato, 1997)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCMAB185AP 04053252746376

Documentation

Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37 SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-CD19 -APC Antibody, clone HD37 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD19 -APC, clone HD37 - 1989783 1989783
Milli-Mark Anti-CD19 -APC, clone HD37 - 2049271 2049271
Milli-Mark Anti-CD19 -APC, clone HD37 - 2064307 2064307
Milli-Mark Anti-CD19 -APC, clone HD37 - 2207210 2207210
Milli-Mark Anti-CD19 -APC, clone HD37 - NRG1761317 NRG1761317
Milli-Mark™ Anti-CD19 -APC, -2580667 2580667
Milli-Mark™ Anti-CD19 -APC, -2724438 2724438
Milli-Mark™ Anti-CD19 -APC, -2772649 2772649
Milli-Mark™ Anti-CD19 -APC, clone HD37 2475030
Milli-Mark™ Anti-CD19 -APC, clone HD37 - 2514238 2514238

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Categories

Life Science Research > Antibodies and Assays > Primary Antibodies