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14-1109 Human Recombinant Histone H2A.Z

14-1109
100 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Key Applications
ACT
Description
Catalogue Number14-1109
DescriptionHuman Recombinant Histone H2A.Z
OverviewFull-length human recombinant H2A.Z expressed in E. Coli and purified by Fast Protein Liquid Chromatography (FPLC ).
Background InformationThe histone variant H2A.Z is a evolutionarily conserved histone variant with a calculated molecular weight of13.5 kDa. This variant replaces conventional histone H2A in a subset of nucleosomes. The nucleosome is the basic unit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histones H2A, H2B, H3 and H4. The histone variant H2AZ has emerged as a key regulator of chromatin function and plays an essential role during mammalian development. H2A.Z is involved in transcriptional regulation, antisilencing, silencing, and genome stability.
References
Product Information
PresentationRecombinant protein in a buffer containing 20mM Tris-Cl pH 7.6, 1mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5mM PMSF and 1mM DTT.
Quality LevelMQ100
Applications
ApplicationHuman recombinant histone H2A.Z expressed in E Coli & purified by Fast Protein Liquid Chromatography (FPLC) & verified mass spectrometry.
Key Applications
  • Activity Assay
Application NotesSuitable for in vitro chromatin assembly and enzyme activity assays
Biological Information
Concentration1.0 µg/µL
HostE. coli
PurityGreater than 98% purity by SDS PAGE
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable at -80ºC for 1 year from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-1109 04053252935039

Documentation

Human Recombinant Histone H2A.Z SDS

Title

Safety Data Sheet (SDS) 

Human Recombinant Histone H2A.Z Certificates of Analysis

TitleLot Number
Human Recombinant Histone H2A.Z - QVP1308211 QVP1308211
Human Recombinant Histone H2A.Z - VP1903210 VP1903210
Human Recombinant Histone H2A.Z - VP2106241 VP2106241
Human Recombinant Histone H2A.Z - VP2208300 VP2208300
Human Recombinant Histone H2A.Z - VP2401090 VP2401090
Human Recombinant Histone H2A.Z Recombinant Proteins VP1709271
Human Recombinant Histone H2A.Z Recombinant Proteins 2897371
Human Recombinant Histone H2A.Z Recombinant Proteins 2879777