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345731 GDF-5, Mouse, Recombinant

345731
Purchase on Sigma-Aldrich

Overview

Key Spec Table

Purity
≥95% by SDS-PAGE

Products

Catalogue NumberPackaging Qty/Pack
345731-50UG Glass bottle 50 μg
Description
OverviewRecombinant, mouse growth differentiation factor 5 (GDF-5) consisting of amino acids 376-495, expressed in E. coli with and without an N-terminal methionine. GDF-5, a member of the bone morphogenetic protein family, is involved in regulation of myogenesis, bone morphogenesis, neuron differentiation and survival, and chondrogenesis regulation.
Catalogue Number345731
Brand Family Calbiochem®
SynonymsCartilage-derived morphogenetic protein 1 (CDMP-1)
References
ReferencesSettle, S.H., Jr., et al. 2003. Dev. Biol. 254, 116.
Massague, J., et al. 2000. Genes and Dev. 14, 627.
FrancisWest, P.H., et al. 1999.
Development 126, 1035. Inada, M., et al. 1996. BBRC 222, 317.
Nishitoh, H., et al. 1996. J. Biol. Chem. 271, 21345.
Storm, E.E., et al. 1994. Nature 368, 639.
Product Information
FormSolid
FormulationLyophilized from 0.2 µm filter-sterilized Acetonitrile, TFA, BSA.
Quality LevelMQ100
Applications
ApplicationGDF-5, Mouse, Recombinant, consists of amino acids 376-495 and is expressed in E. coli with and without an N-terminal methionine. Involved in myogenesis, bone morphogenesis & neuron differentiation.
Biological Information
Biological activityED₅₀ = 1-4 µg/ml as measured by induction of alkaline phosphatase production by ATDC5 mouse chondrogenic cells. (Nakamura, K. et al. 1999. Exp. Cell Res. 250, 351.)
Purity≥95% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg protein
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
345731-50UG 04055977193817