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204910 Complement C9, Human

204910
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Overview

Products

Catalogue NumberPackaging Qty/Pack
204910-250UG Plastic ampoule 250 μg
Description
OverviewNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
Catalogue Number204910
Brand Family Calbiochem®
References
ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
Product Information
CAS number80295-59-6
FormLiquid
FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
Quality LevelMQ200
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥150,000 C9H50 units/mg
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Catalogue Number GTIN
204910-250UG 04055977219890