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ABN105 Anti-Sox11 Antibody

Anti-Sox11 Antibody detects level of Sox11 & has been published & validated for use in 0.

Anti-Sox11 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: SOX11 UniProt Number: P35716
ABN105
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, Immunohistochemistry (Tissue)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN105
DescriptionAnti-Sox11 Antibody
Alternate Names
  • Transcription factor SOX-11
Background InformationSRY box-containing 11 (Sox11) is a neural transcription factor belonging to the DNA-binding high-mobility group (HMG) box protein super family. It is highly expressed during embryonic development and regulates genes involved in neurite growth and survival. Sox11 plays an important role in the formation of sensory neurons and organogenesis. Sox11-deficient mice show defects in multiple organs including the lung, heart, and pancreas. Sox11 also plays a critical role as a tumor suppressor. Epigenetic suppression of the Sox11 gene, primarily through promoter hypermethylation, contributes to various forms of neoplasms. In adults, Sox11 may be involved in the regeneration of neurons after nerve injury by inducing the expression of the small proline rich protein 1a gene (Sprr1a).
References
Product Information
FormatAffinity Purified
Control
  • Mouse brain tissue lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Sox11 Antibody detects level of Sox11 & has been published & validated for use in 0.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Tissue)
Application NotesImmunohistochemistry: A 1:1,000 dilution from a representative lot detected Sox-11 in normal mouse hippocampus and cerebellum tissues.

Western Blot Analysis: A representative lot detecte Sox-11 in human brain tissue lysate.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human Sox-11.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • SOX11
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~57 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

Western Blot Analysis: 0.5 mg/mL of this antibody detected Sox-11 in 10 mg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN105 04053252694790