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AB9610-AF488 Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate

AB9610-AF488
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RIFRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue NumberAB9610-AF488
DescriptionAnti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate
Alternate Names
  • Oligodendrocyte transcription factor 2
  • bHLHe19
  • Olig-2
  • Oligo2
  • RACK17
  • RK17
Background InformationOligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olig-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.
Key Applications
  • Immunofluorescence
Application NotesThe unconjugated antibody (Cat. No. AB9610) is shown to be suitable also for Western blotting, immunocytochemistry, immunohistochemistry, and immunoprecipitation applications.
Biological Information
ImmunogenRecombinant mouse Olig-2.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityThe unconjugated antibody (Cat. No. AB9610) recognizes the ~32 kDa Olig-2 protein by Western blotting.
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Olig2
  • Bhlhb1
Purification MethodAmmonium Sulfate
UniProt Number
Molecular Weight~32 kDa observed.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunofluorescence in mouse brain tissue.

Immunofluorescence Analysis: A 1:50-100 dilution of this antibody detected Olig-2 in mouse brain tissue sections.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9610-AF488 04055977333664

Documentation

Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate Certificates of Analysis

TitleLot Number
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 3187442 3187442
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 3393264 3393264
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 3722614 3722614
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 3930298 3930298
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 3990356 3990356
Anti-Olig-2, Alexa Fluor® 488 Conjugate - 4131130 4131130
Anti-Olig-2, Alexa Fluor® 488 Conjugate -Q2667552 Q2667552
Anti-Olig-2, Alexa Fluor® 488 Conjugate Polyclonal Antibody 3013255
Anti-Olig-2, Alexa Fluor® 488 Conjugate Polyclonal Antibody 2897028
Anti-Olig-2, Alexa Fluor® 488 Conjugate Polyclonal Antibody 3052498