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MABT20 Anti-OL-protocadherin Antibody, clone 5G10

MABT20
100 µg  
Purchase on Sigma-Aldrich

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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, ICC, IHCRPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT20
DescriptionAnti-OL-protocadherin Antibody, clone 5G10
Alternate Names
  • protocadherin 10
  • ortholog of OL-pcdh
Background InformationOL-protocadherin (OL-pc, protocadherin 10) is a transmembrane protein and a member of the cadherin superfamily, which is characterized by its members’ abilities to undergo interactions that are homophilic in nature via their extracellular domain. Several protocadherins have been observed within the nervous system, and a few have been shown to localize at synapses. With OL-pc, the homophilic binding has been shown to stimulate cell aggregation when the protein is introduced into cadherin-deficient cells. Although the function of OL-protocadherin has yet to be elucidated, studies have shown OL-pc to be necessary to axonal normal projection through the ventral telencephalon, where OL-pc shows highest expression at the striatal region.
Product Information
FormatPurified
Control
  • Mouse E13-E14 brain tissue lysate
PresentationPurified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-OL-protocadherin Antibody, clone 5G10 is an antibody against OL-protocadherin for use in WB, IC, IH.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunohistochemistry
Application NotesImmunofluorescence Analysis: The antibody has been shown to detect OL-protocadherin in IF. (Nakao, 2008).

Immunohistochemistry Analysis: The antibody has been shown to detect OL-protocadherin in IH. (Aoki, 2003).
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of mouse OL-protocadherin.
EpitopeCytoplasmic domain
Clone5G10
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRat
SpecificityThe antibody recognizes the cytoplasmic domain of OL-protocadherin.
IsotypeIgG2aκ
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Pcdh10
  • OL-PCDH
  • Pcadh10
Purification MethodProtein G Purified
UniProt Number
UniProt SummarySEQUENCE SIMILARITIES: Contains 6 cadherin domains. (Spearmint SPM002126)
Molecular Weight ~ 130 kDa observed
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse E13-E14 brain tissue lysate.

Western Blot Analysis: 1 µg/mL of the antibody detected OL-protocadherin in 10 µg of mouse E13-E14 brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Global Trade Item Number
Catalogue Number GTIN
MABT20 04053252479458