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MABC713 Anti-KEAP1, clone 7G4B10 Antibody

Anti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.

Anti-KEAP1, clone 7G4B10 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KEAP1, INRF2, KLHL19 UniProt Number: Q14145
MABC713
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIHC, FC, ELISAMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC713
DescriptionAnti-KEAP1, clone 7G4B10 Antibody
Alternate Names
  • Kelch-like ECH-associated protein 1
  • Cytosolic inhibitor of Nrf2
  • INrf2
  • Kelch-like protein 19
  • KEAP1
Background InformationKelch-like ECH-associated protein 1, also known as Cytosolic inhibitor of Nrf2 or INrf2 or Kelch-like protein 19, and encoded by the gene name KEAP1 or INRF2 or KLHL19, acts as a substrate adapter protein for the E3 ubiquitin ligase complex and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 shuttles between the cytoplasm and the nucleus and is widely expressed with high levels found in skeletal muscle.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal in PBS containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.
Key Applications
  • Immunohistochemistry
  • Flow Cytometry
  • ELISA
Application NotesFlow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected KEAP1 in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Biological Information
ImmunogenPurified recombinant fragment of human KEAP1 expressed in E. Coli
Clone7G4B10
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • KEAP1
  • INRF2
  • KLHL19
Purification MethodProtein G Purified
UniProt Number
Molecular Weight70 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KEAP1 in bladder cancer and cerebellum tissues.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC713 04053252957277