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AB5230-200UL Anti-Calcium Channel Antibody, Voltage Gated β3

This Anti-Calcium Channel Antibody, Voltage Gated β3 is validated for use in WB for the detection of Calcium Channel.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Ion Channels & Transporters, Signaling Neuroscience Gene Symbol: CACNB3, CACNLB3, CAB3 UniProt Number: P54284
AB5230-200UL
200 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB5230-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Calcium Channel Antibody, Voltage Gated β3
Alternate Names
  • CAB3
  • Dihydropyridine-sensitive L-type
  • Calcium Channel beta-3 Subunit
  • Voltage-dependent Calcium Channel beta-3 Subunit
References
Product Information
FormatPurified
Control
  • CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
PresentationPurified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, 5% sucrose as a stabilizer and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Quality LevelMQ100
Applications
ApplicationThis Anti-Calcium Channel Antibody, Voltage Gated β3 is validated for use in WB for the detection of Calcium Channel.
Key Applications
  • Western Blotting
Application NotesWestern blot: 1:200-1:300 using ECL on rat brain membranes.

Dilutions should be made using a carrier protein such as BSA (1-3%)

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenA purified peptide corresponding to amino acid residues 463-477 of rabbit Ca beta3 (Accession number P54286).
EpitopeVoltage Gated beta3
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes the full length Ca beta3 protein, not with other known proteins tested so far.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • CACNB3
  • CACNLB3
  • CAB3
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P54284 # The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
SIZE: 484 amino acids; 54532 Da
SUBUNIT: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with CACNA2D4.
TISSUE SPECIFICITY: Expressed mostly in brain, smooth muscle and ovary.
SIMILARITY: SwissProt: P54284 ## Belongs to the calcium channel beta subunit family. & Contains 1 SH3 domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB5230-200UL 04053252402265

Documentation

Anti-Calcium Channel Antibody, Voltage Gated β3 SDS

Title

Safety Data Sheet (SDS) 

Anti-Calcium Channel Antibody, Voltage Gated β3 Certificates of Analysis

TitleLot Number
RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3766680
RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2193329 2193329
RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2318797 2318797

Data Sheet

Title
RABBIT ANTI-CALCIUM CHANNEL BETA 3 AFFINITY PURIFIED POLYCLONAL ANTIBODY