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484100 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem

Potent Cl⁻ channel blocker (IC₅₀ = 100 nM-100 µM), depending on channel subtype and assay method.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NPPB, ANO Blocker II, Anoctamin Blocker II, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II

Primary Target: Cl⁻ channel blocker
484100
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
107254-86-4C₁₆H₁₆N₂O₄

Products

Catalogue NumberPackaging Qty/Pack
484100-10MG Plastic ampoule 10 mg
Description
OverviewPotent Cl– channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
Catalogue Number484100
Brand Family Calbiochem®
SynonymsNPPB, ANO Blocker II, Anoctamin Blocker II, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II
References
ReferencesIllek, B., et al. 1992. Am. J. Physiol. 263, C644.
Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.
Product Information
CAS number107254-86-4
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₆H₁₆N₂O₄
Chemical formulaC₁₆H₁₆N₂O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCl⁻ channel blocker
Primary Target IC<sub>50</sub>100 nM-100 µM as Cl-channel blocker
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
484100-10MG 04055977200676

Documentation

5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem Certificates of Analysis

TitleLot Number
484100

References

Reference overview
Illek, B., et al. 1992. Am. J. Physiol. 263, C644.
Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-April-2015 JSW
SynonymsNPPB, ANO Blocker II, Anoctamin Blocker II, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II
DescriptionPotent Cl- channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
FormYellow solid
CAS number107254-86-4
Chemical formulaC₁₆H₁₆N₂O₄
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (5 mg/ml) or warm Ethanol
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesIllek, B., et al. 1992. Am. J. Physiol. 263, C644.
Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475.
Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398.
Wangermann, P., et al. 1986. Pflugers Arch. 407, S128.