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504637 (S)-MCPG - CAS 150145-89-4 - Calbiochem

(S)-MCPG - CAS 150145-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG

Primary Target: Grup I and II mGlu receptors
504637
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      150145-89-4C₁₀H₁₁NO₄
      Description
      Overview

      This product has been discontinued.



      A non-selective antagonist for group I/II mGlu receptors (minimal values of IC50 reported = 40 and 15 µM for mGlu1 and mGlu2, respectively). Often used as an agent to differentiate excitatory neurotransmissions mediated by glutamate from other neurotransmitters (i.e. dopamine, acetylcholine, and GABA in early brain development). A common component of cocktails for blocking glutamate transmission in brain slice preparation.
      Catalogue Number504637
      Brand Family Calbiochem®
      Synonyms(S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG
      References
      ReferencesFano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
      Wang, W., et al. 2012. J. Physiol. 590, 3743.
      Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
      Neuropharmacol. 38, 1431.
      Product Information
      CAS number150145-89-4
      FormWhite solid
      Hill FormulaC₁₀H₁₁NO₄
      Chemical formulaC₁₀H₁₁NO₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGrup I and II mGlu receptors
      Primary Target IC<sub>50</sub>40 and 15 →M for mGlu₁ and mGlu₂, respectively.
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      504637 0

      Documentation

      (S)-MCPG - CAS 150145-89-4 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Fano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
      Wang, W., et al. 2012. J. Physiol. 590, 3743.
      Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
      Neuropharmacol. 38, 1431.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-June-2013 JSW
      Synonyms(S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG
      DescriptionA non-selective antagonist for group I/II mGlu receptors (minimal values of IC50 reported = 40 and 15 µM for mGlu1 and mGlu2, respectively). Often used as an agent to differentiate excitatory neurotransmissions mediated by glutamate from other neurotransmitters (i.e. dopamine, acetylcholine, and GABA in early brain development). A common component of cocktails for blocking glutamate transmission in brain slice preparation.
      FormWhite solid
      CAS number150145-89-4
      Chemical formulaC₁₀H₁₁NO₄
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (10 mM) or DMSO (10 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesFano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
      Wang, W., et al. 2012. J. Physiol. 590, 3743.
      Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
      Neuropharmacol. 38, 1431.