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528175 Plasminogen, Human Plasma

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528175
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528175-120U
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      Glass bottle 120 u
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      Description
      OverviewNative plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
      Catalogue Number528175
      Brand Family Calbiochem®
      SynonymsProfibrinolysin, Plasma Trypsinogen
      References
      ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
      Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
      Product Information
      CAS number9001-91-6
      Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
      FormLyophilized
      FormulationLyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥120 units/mg protein.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      528175-120U 04055977196436

      Documentation

      Plasminogen, Human Plasma MSDS

      Title

      Safety Data Sheet (SDS) 

      Plasminogen, Human Plasma Certificates of Analysis

      TitleLot Number
      528175

      References

      Reference overview
      Sun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
      Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-May-2008 RFH
      SynonymsProfibrinolysin, Plasma Trypsinogen
      DescriptionNative plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg560.
      FormLyophilized
      FormulationLyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number9001-91-6
      Purity≥95% by SDS-PAGE
      Specific activity≥120 units/mg protein.
      Unit definitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.
      SolubilityH₂O
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.
      Toxicity Irritant
      Merck USA index14, 7521
      ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
      Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.