516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<Synonyms: Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid, Iva-Val-Val-Sta-Ala-Sta
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Overview
Key Spec Table
CAS # | Empirical Formula |
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26305-03-3 | C₃₄H₆₃N₅O₉ |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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516481-100MG |
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Plastic ampoule | 100 mg |
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516481-25MG |
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Plastic ampoule | 25 mg |
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516481-5MG |
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Plastic ampoule | 5 mg |
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Description | |
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Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
Effective concentration: 1.0 µM. | |
Catalogue Number | 516481 |
Brand Family | Calbiochem® |
Synonyms | Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid, Iva-Val-Val-Sta-Ala-Sta |
Product Information | |
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CAS number | 26305-03-3 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₃₄H₆₃N₅O₉ |
Chemical formula | C₃₄H₆₃N₅O₉ |
Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
Reversible | Y |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | cathepsin D |
Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
Safety Information according to GHS | |
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RTECS | SC6155000 |
Global Trade Item Number | |
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Catalogue Number | GTIN |
516481-100MG | 04055977198812 |
516481-25MG | 07790788055837 |
516481-5MG | 04055977198836 |