Millipore Sigma Vibrant Logo

516481 Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
26305-03-3C₃₄H₆₃N₅O₉

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
516481-100MG
Limited Availability
Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Plastic ampoule 100 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      516481-25MG
      Limited Availability
Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 25 mg
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          Request Pricing
          516481-5MG
          Limited Availability
Limited Availability
          In Stock 
          Discontinued
          Limited Quantities Available
          Availability to be confirmed
            Remaining : Will advise
              Remaining : Will advise
              Will advise
              Contact Customer Service
              Contact Customer Service

              Plastic ampoule 5 mg
              Price could not be retrieved
              Minimum Quantity is a multiple of
              Maximum Quantity is
              Upon Order Completion More Information
              You Saved ()
               
              Request Pricing
              Description
              OverviewA reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437).
              Effective concentration: 1.0 µM.
              Catalogue Number516481
              Brand Family Calbiochem®
              SynonymsIsovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid, Iva-Val-Val-Sta-Ala-Sta
              References
              ReferencesIsahara, K., et al. 1999. Neuroscience 91, 233.
              Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
              Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
              Carraway, R.E., et al. 1991. Peptides 12, 107.
              Eid, M., et al. 1981. Biochem. J. 197, 465.
              Umezawa, H., et al. 1970. J. Antibiot. 23, 259.
              Product Information
              CAS number26305-03-3
              ATP CompetitiveN
              FormWhite solid
              Hill FormulaC₃₄H₆₃N₅O₉
              Chemical formulaC₃₄H₆₃N₅O₉
              Optical rotationOptical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
              ReversibleY
              Quality LevelMQ100
              Biological Information
              Primary Targetcathepsin D
              Primary Target IC<sub>50</sub>EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines
              Purity≥98% by HPLC
              Physicochemical Information
              Cell permeableN
              Safety Information according to GHS
              RTECSSC6155000
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Toxicity Standard Handling
              Storage +2°C to +8°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
              Global Trade Item Number
              Catalogue Number GTIN
              516481-100MG 04055977198812
              516481-25MG 07790788055837
              516481-5MG 04055977198836