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444221 MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem

An excellent quenched fluorescence substrate for MMP-1 and MMP-9.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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444221
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Overview

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444221-1MG
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      Description
      OverviewAn excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values.
      Catalogue Number444221
      Brand Family Calbiochem®
      References
      ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
      Product Information
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₄₉H₆₈N₁₄O₁₂S
      Chemical formulaC₄₉H₆₈N₁₄O₁₂S
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-1, MMP-9
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      444221-1MG 04055977205244

      Documentation

      MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      MMP-1/MMP-9 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

      TitleLot Number
      444221

      References

      Reference overview
      Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2007 JSW
      DescriptionAn excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining Ki values. Excitation max: ~365 nm; emission max: ~450 nm.
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₄₉H₆₈N₁₄O₁₂S
      Peptide Sequence{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      ReferencesBickett, D.M., et al. 1993. Anal. Biochem. 212, 58.