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14-909M MELK Protein, active, 250 µg

Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.

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14-909M
250 µg  Also available in 0 μg size (cat#14-909) and in bulk (cat# 14-909-K).
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      Overview

      Replacement Information

      Special Offers

      This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
      Description
      Catalogue Number14-909M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionMELK Protein, active, 250 µg
      OverviewRecombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag
      Alternate Names
      • HPK38
      • PK38
      • pEg3 kinase
      Background InformationMaternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceRecombinant protein of the human MELK gene expressed by baculovirus in insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • MELK
      Purification MethodPurified using glutathione-agarose
      Target Sub-FamilyCAMK
      UniProt Number
      Molecular Weight66 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of KKLNRTLSFAEPG
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 0 μg size (cat#14-909) and in bulk (cat# 14-909-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-909M 04053252468384

      Documentation