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434692 Leukotriene C₄ - CAS 72025-60-6 - Calbiochem

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid

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      Overview

      Key Spec Table

      CAS #Empirical Formula
      72025-60-6C₃₀H₄₇N₃O₉S
      Description
      Overview

      This product has been discontinued.



      Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.
      Catalogue Number434692
      Brand Family Calbiochem®
      SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
      References
      ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
      Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.
      Product Information
      CAS number72025-60-6
      ATP CompetitiveN
      FormLiquid
      FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
      Hill FormulaC₃₀H₄₇N₃O₉S
      Chemical formulaC₃₀H₄₇N₃O₉S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetMicrosomal glutathione transferase-1
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSMB9143500
      Safety Information
      R PhraseR: 11-23/24/25-39/23/24/25

      Highly flammable.
      Toxic by inhalation, in contact with skin and if swallowed.
      Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
      S PhraseS: 16-7-36/37-45

      Keep away from sources of ignition - No Smoking.
      Keep container tightly closed.
      Wear suitable protective clothing and gloves.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Flammable
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      434692 0