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IF014 Interferon-β Protein, Recombinant human

Recombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).

Interferon-β Protein, Recombinant human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture UniProt Number: P01574 Entrez Gene Number: NM_002176.2
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IF014
100000 units  
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      Overview

      Key Spec Table

      Key ApplicationsSpeciesSourcePurity
      CULTHuman cDNA obtained from human fibroblast mRNA expressed in CHO cells.> / = 95%, one N-glycosylation site
      Description
      Catalogue NumberIF014
      ReplacesIF008
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionInterferon-β Protein, Recombinant human
      OverviewRecombinant Human Interferon Beta 1a (Hu-IFNbeta 1a). Molecular weight is ~23 kDa.
      Alternate Names
      • Fibroblast Interferon
      Product Information
      PresentationFrozen liquid in 50 mM NaOAc, pH 5.5, containing 0.1% BSA.
      Quality LevelMQ100
      Applications
      ApplicationRecombinant Human Interferon Beta 1a (Hu-IFNbeta 1a).
      Key Applications
      • Cell Culture
      Biological Information
      Concentration1 x 106 units/mL
      Purity> / = 95%, one N-glycosylation site
      SourcecDNA obtained from human fibroblast mRNA expressed in CHO cells.
      Specific ActivitySPECIFIC ACTIVITY: 3.99 x 108 units/mg <br /><br />BIOACTIVITY: Determined by assaying inhibition of virus-induced cytopathic effect. In this antiviral assay for interferon, about 1 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for human interferon beta (Hu-IFNbeta) provided by the National Institutes of Health. Unit of activity measured on VERO cells with vesicular stomatitis virus (VSV).
      Entrez Gene Number
      Gene Symbol
      • IFNB1
      • IFN-beta
      • IFF
      • IFB
      • IFNB
      • MGC96956
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01574 # Has antiviral, antibacterial and anticancer activities.
      SIZE: 187 amino acids; 22294 Da
      SUBUNIT: Monomer.
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P01574 ## Belongs to the alpha/beta interferon family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsAfter receipt, this product should be kept at -70°C or below for retention of full activity.
      Thaw product vial by incubation cold tap water until just thawed. Thawed IFNβ should be
      stored in working aliquots at -70°C for up to six months. Avoid multiple freeze/thaw cycles.
      Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the
      product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
      Packaging Information
      Material Size100000 units
      Global Trade Item Number
      Catalogue Number GTIN
      IF014 04053252470646