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508436 InSolution™ AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem

A 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride in H₂O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: AEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl

Primary Target: serine proteases
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508436
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S • HCl

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      Description
      Catalogue Number508436
      Brand Family Calbiochem®
      SynonymsAEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl
      References
      ReferencesCitron, M., et al. 1996. Neuron 17, 171.
      Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
      Mintz, G.R. 1993. BioPharm. 6, 34.
      Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
      Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
      Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
      Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
      Product Information
      CAS number30827-99-7
      FormLiquid
      FormulationA 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride (Cat. No. 101500) in H₂O.
      Hill FormulaC₈H₁₀FNO₂S • HCl
      Chemical formulaC₈H₁₀FNO₂S • HCl
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetserine proteases
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 1 year at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.08436.0001 04055977261950

      Documentation

      InSolution™ AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Citron, M., et al. 1996. Neuron 17, 171.
      Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
      Mintz, G.R. 1993. BioPharm. 6, 34.
      Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
      Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
      Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
      Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-January-2014 JSW
      SynonymsAEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl
      DescriptionSpecific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications.
      FormLiquid
      FormulationA 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride (Cat. No. 101500) in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number30827-99-7
      Chemical formulaC₈H₁₀FNO₂S • HCl
      Structure formulaStructure formula
      Purity≥97% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 1 year at -20°C.
      Toxicity Standard Handling
      ReferencesCitron, M., et al. 1996. Neuron 17, 171.
      Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
      Mintz, G.R. 1993. BioPharm. 6, 34.
      Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
      Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
      Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
      Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.