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368067 Granzyme B Substrate VIII, Colorimetric - CAS 216757-29-8 - Calbiochem

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368067-5MG
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      Description
      OverviewA colorimetric substrate for granzyme B (kcat/Km = 6.6 x 104 M-1s-1). Cleavage of pNA is monitored colorimetrically at ~405 nm (ε = 9,160 M-1cm-1).
      Catalogue Number368067
      Brand Family Calbiochem®
      SynonymsAc-IEPD-pNA
      References
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
      Product Information
      CAS number216757-29-8
      ATP CompetitiveN
      FormWhite lyophilized solid
      Hill FormulaC₂₈H₃₈N₆O₁₁
      Chemical formulaC₂₈H₃₈N₆O₁₁
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetColorimetric substrate for granzyme B
      Primary Target IC<sub>50</sub>kcat/Km = 6.6 x 104 M⁻¹ sec⁻¹ as substrate for granzyme B
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Ile-Glu-Pro-Asp-pNA
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      368067-5MG 04055977192186