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345802 Gc-Globulin, Mixed Type, Human Plasma

Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.

Gc-Globulin, Mixed Type, Human Plasma MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DBP, Vitamin D Binding Protein, Group-specific Component

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345802
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      Description
      OverviewNative Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.
      Catalogue Number345802
      Brand Family Calbiochem®
      SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
      References
      ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
      Lee, W.M., et al. 1987. Hepatology 7, 825.
      Machii, T., et al. 1986. Acta Haematol. 75, 26.
      Product Information
      CAS number68476-36-8
      FormSolid
      FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
      Quality LevelMQ100
      Applications
      ApplicationGc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      345802-1MG 04055977194050

      Documentation

      Gc-Globulin, Mixed Type, Human Plasma MSDS

      Title

      Safety Data Sheet (SDS) 

      Gc-Globulin, Mixed Type, Human Plasma Certificates of Analysis

      TitleLot Number
      345802

      References

      Reference overview
      Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
      Lee, W.M., et al. 1987. Hepatology 7, 825.
      Machii, T., et al. 1986. Acta Haematol. 75, 26.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-June-2008 RFH
      SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
      DescriptionNative Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.
      FormSolid
      FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      CAS number68476-36-8
      Purity≥95% by SDS-PAGE
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
      Toxicity Standard Handling
      ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
      Lee, W.M., et al. 1987. Hepatology 7, 825.
      Machii, T., et al. 1986. Acta Haematol. 75, 26.