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05-683 Anti-Mps1 Antibody, CT, clone 4-112-3

Anti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.

Anti-Mps1 Antibody, CT, clone 4-112-3 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Cell Cycle, DNA Replication & Repair Gene Symbol: TTK, PYT, MPS1L1, ESK, FLJ38280 UniProt Number: P33981
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05-683
200 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIP, WB, ICCMPurifiedMonoclonal Antibody
      Description
      Catalogue Number05-683
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Mps1 Antibody, CT, clone 4-112-3
      OverviewThis antibody is known to inhibit the autophos-phorylation/kinase activity of Mps1; Mps1 was previously known as TTK/PYK
      References
      Product Information
      FormatPurified
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
      Quality LevelMQ100
      Applications
      ApplicationAnti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunocytochemistry
      Biological Information
      ImmunogenHis-tagged fusion protein corresponding to amino acids 3-856 of human Mps1
      Cloneclone 4-112-3
      HostMouse
      SpecificityMps1
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TTK
      • PYT
      • MPS1L1
      • ESK
      • FLJ38280
      Purification MethodProtein G Chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P33981 # Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation.
      SIZE: 857 amino acids; 97072 Da
      TISSUE SPECIFICITY: Present in rapidly proliferating cell lines.
      SIMILARITY: SwissProt: P33981 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
      Molecular Weight97kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on HeLa total cell extract
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      05-683 04053252471278

      Documentation

      Anti-Mps1 Antibody, CT, clone 4-112-3 MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Mps1 Antibody, CT, clone 4-112-3 Certificates of Analysis

      TitleLot Number
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) 3090796
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) 2899918
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2250526 2250526
      Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2361826 2361826
      Anti-Mps1, CT, clone 4-112-3 - 22462 22462
      Anti-Mps1, CT, clone 4-112-3 - 3164847 3164847
      Anti-Mps1, CT, clone 4-112-3 - 3708801 3708801
      Anti-Mps1, CT, clone 4-112-3 - 4008086 4008086
      Anti-Mps1, CT, clone 4-112-3 - DAM1564471 DAM1564471
      Anti-Mps1, CT, clone 4-112-3 - DAM1731736 DAM1731736
      Show more

      References

      Reference overviewPub Med ID
      Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication.
      Stucke, Volker M, et al.
      EMBO J., 21: 1723-32 (2002)  2002

      		11927556 11927556

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies