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ABT139 Anti-Integrin alpha8 Antibody

This Integrin alpha8 antibody is validated for use in IHC for the detection of the Integrin alpha8 protein.

Anti-Integrin alpha8 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: ITGA8 UniProt Number: P53708
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ABT139
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT139
      DescriptionAnti-Integrin alpha8 Antibody
      Alternate Names
      • Integrin alpha-8
      • Integrin alpha-8 heavy chain
      • Integrin alpha-8 light chain
      Background InformationIntegrin alpha-8 is involved in the development of kidney, and possibly other organs, through the organization of mesenchymal cells into epithelial structures. As a neural receptor it recognizes several ligands including TNC, FN1, SPP1 TGFB1, TGFB3, VTN, and mediates cell-cell interactions and adhesion. Integrin alpha-8 is expressed in mesenchymal cells, alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells.
      Product Information
      FormatAffinity Purified
      Control
      • Human kidney and human lung tissue
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Integrin alpha8 antibody is validated for use in IHC for the detection of the Integrin alpha8 protein.
      Key Applications
      • Immunohistochemistry (Paraffin)
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of human Integrin alpha8.
      EpitopeExtracellular domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the extracellular domain of Integrin alpha8.
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Other homologies: Mouse (88% sequence homology) and Rat (89% sequence homology).
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ITGA8
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight117 kDa calculated
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human kidney and human lung tissue.

      Imunnohistochemistry Analysis: A 1:500-2,000 dilution of this antibody detected Integrin alpha8 in human kidney and human lung tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      ABT139 04053252858260