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116833 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-CPT-2ʹ-O-Me-cAMP, Na

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      Overview

      Replacement Information

      Key Spec Table

      Empirical Formula
      C₁₇H₁₆ClN₅O₆PS • Na
      Description
      Overview

      This product has been discontinued.



      A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA.
      Note: 5 µmol = 2.54 mg.
      Catalogue Number116833
      Brand Family Calbiochem®
      Synonyms8-CPT-2ʹ-O-Me-cAMP, Na
      References
      ReferencesKang, G., et al. 2003. J. Biol. Chem. 278, 8279.
      Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.
      Product Information
      DeclarationSold under license of European Patent Application 02/077,219.0.
      FormLyophilized
      Hill FormulaC₁₇H₁₆ClN₅O₆PS • Na
      Chemical formulaC₁₇H₁₆ClN₅O₆PS • Na
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      116833 0

      Documentation

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2ʹ-O-Methyl-, Sodium Salt - Calbiochem Certificates of Analysis

      TitleLot Number
      116833

      References

      Reference overview
      Kang, G., et al. 2003. J. Biol. Chem. 278, 8279.
      Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-June-2013
      Synonyms8-CPT-2ʹ-O-Me-cAMP, Na
      DescriptionA potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) (also called cAMP-guanine nucleotide-exchange factors or cAMP-GEF) in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. 5 µmol = 2.54 mg. λmax = 282 nm.
      FormLyophilized
      Chemical formulaC₁₇H₁₆ClN₅O₆PS • Na
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (10 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKang, G., et al. 2003. J. Biol. Chem. 278, 8279.
      Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.