Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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Description
Overview
Potent selective high affinity blocker of P-type Ca2+ channels (Kd = 2 nM). Reported to abolish nicotine-evoked responses in cardiac vagal neurons (˜100 nM).
Catalogue Number
121974
Brand Family
Calbiochem®
Synonyms
ω-Aga-IVA
References
References
Wang, J., et al. 2001. J. Neurophysiol.85, 164. Nooney, J.M., and Lodge, D. 1996. Eur. J. Pharmacol. 306, 41. Mintz, I.M., et al. 1992. Nature355, 827. Turner, T.J., et al. 1992. Science258, 310.
Following reconstitution, aliquot and refrigerate (4°C) for short-term storage or freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 3 months at -20°C.
Wang, J., et al. 2001. J. Neurophysiol.85, 164. Nooney, J.M., and Lodge, D. 1996. Eur. J. Pharmacol. 306, 41. Mintz, I.M., et al. 1992. Nature355, 827. Turner, T.J., et al. 1992. Science258, 310.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
31-May-2011 RB
Synonyms
ω-Aga-IVA
Description
A potent and selective blocker of the P-type voltage-dependent Ca2+ channels (Kd = 2 nM).
Potently inhibits the Cav2.1 channel currents expressed in HEK293 cells.
Solubility
H₂O (1 mg/ml) or Saline (1 mg/ml)
Storage
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and refrigerate (4°C) for short-term storage or freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 3 months at -20°C.
Toxicity
Harmful
References
Wang, J., et al. 2001. J. Neurophysiol.85, 164. Nooney, J.M., and Lodge, D. 1996. Eur. J. Pharmacol. 306, 41. Mintz, I.M., et al. 1992. Nature355, 827. Turner, T.J., et al. 1992. Science258, 310.
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