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500936 Vitamina D₃ (colecalciferol) crist. (1 g = 40 Mio.I.U.)

EMPROVE® ESSENTIAL Ph Eur,BP,USP

Vitamina D₃ (colecalciferol) crist. (1 g = 40 Mio.I.U.) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Colecalciferol, Cholecalciferol

CAS #: 67-97-0 EC Number: 200-673-2 Molar Mass: 384.65 g/mol Hill Formula: C₂₇H₄₄O Grade: Ph Eur,BP,USP
500936
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Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
67-97-0200-673-2C₂₇H₄₄O384.65 g/molPh Eur,BP,USP

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      5009360100
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          Description
          Catalogue Number500936
          SynonymsColecalciferol, Cholecalciferol
          References
          Product Information
          CAS number67-97-0
          EC index number603-180-00-4
          EC number200-673-2
          GradePh Eur,BP,USP
          Hill FormulaC₂₇H₄₄O
          Molar Mass384.65 g/mol
          HS Code2936 29 21
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Melting Point84 - 85 °C
          Solubility<0.1 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 5 - 50 mg/kg
          LD 50 dermalLD50 Rat 61 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H300 + H310 + H330: Mortal în caz de înghiţire, în contact cu pielea sau prin inhalare.
          H372: Provoacă leziuni ale organelor în caz de expunere prelungită sau repetată în caz de înghiţire.
          Precautionary Statement(s)P260: Nu inspiraţi praful.
          P262: Evitaţi orice contact cu ochii, pielea sau îmbrăcămintea.
          P280: Purtaţi mănuşi de protecţie/ îmbrăcăminte de protecţie.
          P302 + P352 + P310: ÎN CAZ DE CONTACT CU PIELEA: spălați cu multă apă. Sunați imediat la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic.
          P304 + P340 + P310: ÎN CAZ DE INHALARE: transportați persoana la aer liber și mențineți-o într-o poziție confortabilă pentru respirație. Sunați imediat la un CENTRU DE INFORMARE TOXICOLOGICĂ/un medic.
          P314: Consultaţi medicul, dacă nu vă simţiţi bine.
          Signal WordPericol
          RTECSVS2900000
          Storage class6.1A Materiale combustibile, toxicitate acută Categoria 1 şi 2 /materiale periculoase foarte toxice
          WGKWGK 2 substanţe cu potenţial specific de poluare a apei
          Disposal9
          Compusii cancerigeni si compusii inflamabili marcati ca "toxici" sau "foarte toxici": container F. Alchili-sulfatii sunt cancerigeni. Luati masuri speciale pentru a evita inhalarea sau contactul cu pielea. Pentru neutralizarea alchil-sulfatilor, acestia se adauga in picaturi (cu o palnie de picurare) in solutie concentrata de amoniac racita cu gheata (Cod Merck 105426) agitand puternic. Inainte de colectarea in containerul D, verificati pH-ul cu strip-uri indicatoare pH, universale (Cod Merck 109535).
          Safety Information
          Categories of dangerfoarte toxic
          Product Usage Statements
          Storage and Shipping Information
          StorageA se depozita între +2°C la +8°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 2811 , 6.1, I
          Declaration (transport by air) IATA-DGRUN 2811 , 6.1, I
          Declaration (transport by sea) IMDG-CodeUN 2811 , 6.1, I
          Supplemental Information
          Specifications
          Assay (HPLC)97.0 - 102.0 %
          Identity (IR-spectrum)passes test
          Identity (HPLC)passes test
          Identity (UV-spectrum (USP))passes test
          Spec. rotation [α²0/D (8 g/l; (aldehyde-free alcohol 96 %))+105 - +112 °
          Spec. rotation [α²5/D (5 g/l; ethanol)+105 - +112 °
          As (Arsenic)≤ 3 ppm
          Cu (Copper)≤ 25 ppm
          Pb (Lead)≤ 10 ppm
          Zn (Zinc)≤ 25 ppm
          Acetone (HS-GC)≤ 5000 ppm
          Hexane (HS-GC)≤ 290 ppm
          Methanol (HS-GC)≤ 3000 ppm
          Methylformate (HS-GC)≤ 1000 ppm
          Pyridine (HS-GC)≤ 200 ppm
          Other residual solvents (ICH Q3C)excluded by production process
          Related substances (HPLC) (trans-cholecalciferol)≤ 0.1 %
          Related substances (HPLC) (largest unspecified impurity)≤ 0.10 %
          Related substances (HPLC) (Sum of all impurities)≤ 1.0 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph Eur, BP, USP
          Global Trade Item Number
          Catalogue Number GTIN
          5009360010 04022536257310
          5009360100 04022536257327

          Documentation

          Emprove Dossier

          TitleVersion
          8.0

          Quality Management Dossier (Open Access)

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          Operational Excellence Dossier

          Title

          Vitamina D₃ (colecalciferol) crist. (1 g = 40 Mio.I.U.) MSDS

          Title

          Safety Data Sheet (SDS) 

          Vitamina D₃ (colecalciferol) crist. (1 g = 40 Mio.I.U.) Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          5009360010 Glass bottlePDF Specification Document
          5009360100 Glass bottlePDF Specification Document

          Certificates

          Title